hrp0095p2-4 | Adrenals and HPA Axis | ESPE2022

The utility of random cortisol in identifying neonatal primary adrenal insufficiency.

Pyle-Eilola Amy , Chaudhari Monika , Bulan Ayse , Mamilly Leena , Henry Rohan

While it has been established that within the first 4 months of life there is an absence of the circadian rhythm guiding cortisol secretion, it remains unclear if a random serum cortisol (rSC) level is useful in diagnosing neonatal primary adrenal insufficiency (PAI). The objective of this study is to determine the utility of rSC in determining PAI within the first 4 months of life. This is a retrospective chart review of subjects who had rSC collection and high dose cosyntrop...